1.NounAny (hypothesised) primordial organism in which the relationship between genotype and phenotype was still evolving.
"It is sometimes assumed that the concepts of LUCA and progenote are the same by definition; more correctly, it is hypothesised that LUCA was a progenote."
2.NounThe most recent common ancestor to all organisms now living on Earth; LUCA; specifically, the most recent progenitor of all archaea, bacteria and eukaryotes.