1.VerbTo make complex; to modify so as to make something intricate or difficult.
2.VerbTo involve in a convoluted matter.
"Don't complicate yourself in issues that are beyond the scope of your understanding.; John has been complicated in the affair by new tapes that surfaced.; The DA has made every effort to complicate me in the scandal."
3.VerbTo coexist with (another disease) creating a complication.