1.NounAn antibiotic C52H76O24 with antineoplastic activity which is produced by three bacteria of the genus Streptomyces (Streptomyces argillaceus, Streptomyces tanashiensis, and Streptomyces plicatus), acts by inhibiting DNA transcription and replication, and is administered intravenously especially in the treatment of malignant tumors of the testes or in the treatment of hypercalcemia and hypercalciuria associated with advanced neoplastic disease.