Definitions
1.nounLoss of hope; utter hopelessness; complete despondency."He turned around in despair, aware that he was not going to survive"
2.nounThat which causes despair.
3.nounThat which is despaired of.
4.verbTo give up as beyond hope or expectation; to despair of.
5.verbTo cause to despair.
6.verb(often with “of”) To be hopeless; to have no hope; to give up all hope or expectation.